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Modern HPLC for Practicing Scientists

Modern HPLC for Practicing ScientistsAuthor: Michael W. Dong
Publisher: Wiley-Interscience

List Price: $69.95
Buy New: $49.94
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New (21) Used (11) from $49.94

Seller: sbd-
Rating: 5.0 out of 5 stars 8 reviews
Sales Rank: 184581

Media: Paperback
Edition: 1st
Pages: 304
Number Of Items: 1
Shipping Weight (lbs): 0.9
Dimensions (in): 9.2 x 6.1 x 0.7

ISBN: 047172789X
Dewey Decimal Number: 615.19
EAN: 9780471727897
ASIN: 047172789X

Publication Date: June 12, 2006
Availability: Usually ships in 1-2 business days

Also Available In:

  • Kindle Edition - Modern HPLC for Practicing Scientists

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Editorial Reviews:

Product Description
A comprehesive yet concise guide to Modern HPLC

Written for practitioners by a practitioner, Modern HPLC for Practicing Scientists is a concise text which presents the most important High-Performance Liquid Chromatography (HPLC) fundamentals, applications, and developments. It describes basic theory and terminology for the novice, and reviews relevant concepts, best practices, and modern trends for the experienced practitioner. Moreover, the book serves well as an updated reference guide for busy laboratory analysts and researchers.

Topics covered include:

  • HPLC operation
  • Method development
  • Maintenance and troubleshooting
  • Modern trends in HPLC such as quick-turnaround and "greener" methods
  • Regulatory aspects

While broad in scope, this book focuses particularly on reversed-phase HPLC, the most common separation mode, and on applications for the pharmaceutical industry, the largest user segment. Accessible to both novice and intermedate HPLC users, information is delivered in a straightforward manner illustrated with an abundance of diagrams, chromatograms, tables, and case studies, and supported with selected key references and Web resources.

With intuitive explanations and clear figures, Modern HPLC for Practicing Scientists is an essential resource for practitioners of all levels who need to understand and utilize this versatile analytical technology.


Customer Reviews:
Showing reviews 1-5 of 8



5 out of 5 stars A User's Guide for All Levels   October 24, 2007
Lorraine M. Henriques (Portland, OR)
2 out of 2 found this review helpful

In this concise and very affordable book, Dr. Dong has compiled the most important concepts for anyone interested in the fundamentals of HPLC. He has also taken great care to provide clear illustrations to bring across these concepts, which, like many images, speak a thousand words. In a world inundated with almost too much information, it is very refreshing to have a text in hand that one can read through, understand, and put to use in a short amount of time. As a former research scientist turned Technical Sales Rep, I appreciate that I can put this book to work for me. Every chromatographer, new or experienced, needs to have this book on their shelf, or better yet, on top of the lab bench.


5 out of 5 stars MOdern HPLC for Practicing Scientists   June 3, 2007
F. Lin (Short Hills, NJ)
4 out of 4 found this review helpful

HPLC has become one of the most widely applied chemical analytical techniques in the pharmaceutical industry. Dr Dong's book, Modern HPLC for Practicing Scientists, provides excellent source of information and knowledge for both beginners and highly experienced professionals who utilize this analytical tool. Chapter 1 presents an overview of chromatographic principles while the 2nd chapter deals with fundamental aspects of HPLC and considerations that enhance efficient separation. In chapter 3, Dr. Dong discusses the chromatographic column both from theoretical perspectives and applications. This is very valuable to practicing scientists.

In Chapter 4, the book provides a concise overview of HPLC instrumentation, operating principles as well as recent advances in instrumentation such as Waters Acquity UPLCTM (Chapter 11). A lot of information is provided on practical issues associated with the use of HPLC systems and the pictures and illustrations make their understanding much easier.

Chapter 5 provides a hands-on approach to HPLC analysis including mobile phase preparation and parameter optimization. This is a great chapter for a novel analyst who is often saddled with numerous options on the choice of HPLC parameters. Dr. Dong's attention to details makes it possible even for the novice chromatographer to undertake a full HPLC procedure with little or no supervision

Although Chapters 6 and 7 deal with applications in the pharmaceutical, food and environmental industries, the practicing scientist who this text is best suited for, would benefit more by integrating information from these chapters with the fundamental and practical concepts documented in the earlier chapters.

The inclusion of method development and regulatory issues with respect to HPLC techniques and applications in chapters 8 and 9 is particularly commendable. Industrial R & D scientists who are not only challenged to develop and optimize methods but also work within the constraints of regulatory agencies would find these chapters immensely rewarding. These chapters provide hands-on guidance for laboratory scientists in the pharmaceutical and other regulatory industries.

Chapter 10, dealing with troubleshooting is one of the special attributes of this book. This chapter provides quick fix approach to resolving some of the HPLC's often encountered problems. This chapter is bound to save some cost because more often than not, the HPLC analyst tend to vainly envisage and explore more catastrophic problems ignoring the simple remedies that are succinctly documented in Chapter 10.

Overall, Dr. Dong's book is very well written. Each aspect of the text is clearly and succinctly presented, making it easy to understand. The chapter on maintenance and troubleshooting guide (Chapter 11) should be a great asset. Dr. Dong has managed, in a very basic but meticulous manner, to produce an essential text for both the novice and experienced HPLC practitioner in the pharmaceutical industry.



5 out of 5 stars Excellent book   May 10, 2007
Armando-Malwani (MN, USA)
1 out of 1 found this review helpful

This is one of the best books on HPLC I have encountered. Gives an extremely thorough introduction to everything you should know inorder to get started and work confidently with this indispensible technology. Invaluable for the graduate student who wants to go hands on.


5 out of 5 stars Excellent reference   October 17, 2006
K HuynhBa (DE)
1 out of 1 found this review helpful

This is an excellent book that all liquid chromatographers should have. It covers all aspects of HPLC from theories to instrument to applications. It would benefit all levels of analytical scientists in their day-to-day operations. The book is informative and concise. It also includes an excellent list of references for further interest. I think Michael Dong has done it once again!!! Quite an impressive book! and the price can't be beat!


5 out of 5 stars A great reference/guide for HPLC practitioners   October 2, 2006
Wilhad M. Reuter
1 out of 1 found this review helpful

This is quite a comprehensive treatise on the topic of HPLC. The intended audience is the novice/intermediate and it certainly hit the mark. It is quite apparent that the wealth of recommendations/pointers/guidelines comes from someone very familiar with this topic. This book should be of great help to many aspiring LC chromatographers and should also serve as a valuable reference to those that are already comfortable in this field. - Wilhad M Reuter (PerkinElmer LAS)

Showing reviews 1-5 of 8





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